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ABSTRACT

Objetves

To analyze the performance of three in-clinic test kits for the detection of
protective serum antibody titers against:

Method

Serum samples from 46 vaccinated dogs, were tested for the presence of protective antibodies using three commercial in-clinic test kits:

STUDY DESIGN AND METHOD

Prospective comparative study (fresh plasma samples)

  • 5 veterinary clinics (4 in the Netherlands and one in Belgium).
  • 7-10 healthy adult dogs with known vaccination history.
  • Tests performed sequentially. Results recorded in results-form + photographic documentation.
  • Aliquot of plasma sent frozen for gold standard iter test (SN and HI) AHDC, Cornell University.

RESULTS

Conclusions from this trial

and FasTest kits have excellent agreement between themselves and with the Gold standard laboratory methods.

RapidStatus kit generated results different to those of  , FastTest and the reference laboratory gold standard test.

High rate of false negatives could lead to unnecessary revaccination of dogs.

Why using ?

Added value

Grupo 9486

Vaccicheck measures CAV Ab while the FasTest does not. Some veterinarian dismisses the importance of CAV, it is still part of the recommendation by the WSAVA Guidelines and this disease is still relevant.

Grupo 9485

Results have no diagnostic value after 20 min. This is especially important when there is a need for a second review of the results.

Grupo 9484

Only Vaccicheck have been evaluated and approved by the USDA (USA) and MAFF (Japan) i.e the correlation between the titers.